Figure. Relative Risks for the Association Between Coffee Consumption for Individual Cohort Studies and All Cohort Studies Combined
Relative risks were incidence density ratios from proportional hazards models, except for the study by van Dam et al,30 which used odds ratios obtained by logistic regression analysis to estimate relative risks. CI indicates confidence interval. The size of the data markers (squares) corresponds to the weight of the study in the meta-analysis.
he current meta-analysis of cohort studies supports a significant inverse association between coffee consumption and risk of type 2 diabetes. Participants who drank 4 to 6 cups and more than 6 to 7 cups of coffee per day had a 28% and 35% lower risk of type 2 diabetes compared with those who drank less than 2 cups per day. Similar inverse associations between coffee consumption and IGT or type 2 diabetes were observed in cross-sectional studies.